The CHERRIES project will support Responsible Research and Innovation (RRI) policy experiments in the healthcare sector in three European territories – in Murcia (ES), Örebro (SE) and the Republic of Cyprus (CY). The CHERRIES experiments address opportunities and challenges associated with the role of demand at the crossroads of challenge-oriented, economy-enhancing, and sector-specific policy making within the healthcare sector, thereby addressing the SGC of health, demographic change and wellbeing. The project aims to create more open, inclusive, and self-sustaining R&I ecosystems by ensuring bottom-up involvement of all kind of citizens, irrespective of their age, gender, ethnicity and socio-economic background.